Zearalenone-<wbr/><sup>13</sup>C<sub>18</sub>

Zearalenone-13C18

CAT N°: 31288
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Zearalenone-13C18 is intended for use as an internal standard for the quantification of zearalenone (Item No. 11353) by GC- or LC-MS. Zearalenone is a mycotoxin that has been found in Fusarium and has estrogenic activities.{20562} It binds to human estrogen receptor ? (ER?) and ER? (IC50s = 9 and 5.8 nM, respectively).{54526} Zearalenone induces precocious development of mammary tissues in young female pigs and prepucial enlargement in young male pigs.{20560} Zearalenone (1.5-5 mg/kg of diet) induces hyperestrogenism in pigs. It also induces degeneration of meiotic chromatin in oocytes and reduces fertility in pigs when administered at a dose of 200 µg/kg.{20561} Zearalenone has been found as a contaminant in wheat, maize, and barley and livestock feeds.{20560,20561}

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