Z-FA-FMK

Z-FA-FMK

CAT N°: 14462
Price:

From 109.00 92.65

Z-FA-FMK is an irreversible inhibitor of cysteine proteases, including cathepsins B, L, and S, cruzain, and papain.{22853} It also inhibits effector caspases-2, -3, -6, and -7 (IC50 = 6-32 µM) without affecting the initiator caspases-8 and -10.{22857} Z-FA-FMK also modulates infection by certain bacteria, parasites, and viruses.{22854,22856,22855} It can be used both in cells and in vivo.{22856,22855}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-[(1S)-2-[(3-fluoro-1-methyl-2-oxopropyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-carbamic acid, phenylmethyl ester
  • Correlated keywords
    • 105637-38-5 inhibitors inhibits inhibitions apoptosis ZFAFMK Z FA FMK cysteines proteases cathepsins B L S cruzain papain caspases 2 3 6 7 8 10 caspase-2 caspase-3 caspase-6 caspase-7 infections bacteria parasites viruses modulates irreversible effectors initiators caspase-8 caspase-10 cells in vivo deaths
  • Product Overview:
    Z-FA-FMK is an irreversible inhibitor of cysteine proteases, including cathepsins B, L, and S, cruzain, and papain.{22853} It also inhibits effector caspases-2, -3, -6, and -7 (IC50 = 6-32 µM) without affecting the initiator caspases-8 and -10.{22857} Z-FA-FMK also modulates infection by certain bacteria, parasites, and viruses.{22854,22856,22855} It can be used both in cells and in vivo.{22856,22855}

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