Y11

Y11

CAT N°: 18521
Price:

From 66.00 56.10

Focal adhesion kinases (FAKs) are non-receptor tyrosine kinases that play roles in regulating diverse processes, including cell adhesion, spreading, migration, proliferation, and apoptosis. They are over-expressed in many types of cancer. Y11 inhibits FAK1 autophosphorylation by blocking phosphorylation of Y397.{23133} At 100 µM, it was shown to decrease cell viability of T47D breast cancer and C8161 melanoma cell lines.{23133}

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