Visnagin

Visnagin

CAT N°: 34140
Price:

From 46.00 39.10

Visnagin is a polyketide synthase-derived furanochromone originally isolated from A. visnaga that has diverse biological activities.{60512,60513,60514,60515,60516} It inhibits the germination and growth of ryegrass (IC50s = 502 and 214 µM, respectively).{60513} Visnagin (100 µg/ml) is cytotoxic to, and induces apoptosis in, HT-144 melanoma cells.{60514} It reduces LPS-stimulated increases in the secretion of TNF-?, IL-1?, and IFN-? in BV-2 microglial cells when used at concentrations of 50 and 100 µM.{60515} Visnagin (25 mg/kg) protects against cardiomyopathy induced by doxorubicin (Item No. 15007) in mice.{60516}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 4-methoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-one
  • Correlated keywords
    • Desmethoxykhellin Desmethoxy-khellin NSC100593 Visnagidin Visnagine furano-chromone Ammi HT144 TNF? IL1? IFN? BV2
  • Product Overview:
    Visnagin is a polyketide synthase-derived furanochromone originally isolated from A. visnaga that has diverse biological activities.{60512,60513,60514,60515,60516} It inhibits the germination and growth of ryegrass (IC50s = 502 and 214 µM, respectively).{60513} Visnagin (100 µg/ml) is cytotoxic to, and induces apoptosis in, HT-144 melanoma cells.{60514} It reduces LPS-stimulated increases in the secretion of TNF-?, IL-1?, and IFN-? in BV-2 microglial cells when used at concentrations of 50 and 100 µM.{60515} Visnagin (25 mg/kg) protects against cardiomyopathy induced by doxorubicin (Item No. 15007) in mice.{60516}

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