Virginiamycin S1

Virginiamycin S1

CAT N°: 17455
Price:

From 524.00 445.40

Virginiamycin S1 is a macrolide antibiotic that is a component of the virginiamycin complex (Item No. 14503), which also contains virginiamycin M1 (Item No. 9002172).{39373} It is a member of the streptogramin B group of antibiotics, which bind the 50S ribosomal subunit at the peptidyl transferase center to inhibit initiation and translocation.{27765} They show good bactericidal activity against methicillin-resistant S. aureus (MRSA), although resistance in MRSA is conferred by the cfr gene.{27765,28231} Virginiamycin S1 acts synergistically with virginiamycin M1 to irreversibly inhibit protein synthesis in bacteria.{23008}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-((6R,9S,10R,13S,15aS,22S,24aS)-22-benzyl-6-ethyl-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyldocosahydro-12H-pyrido[2,1-f]pyrrolo[2,1-l][1]oxa[4,7,10,13,16]pentaazacyclononadecin-9-yl)-3-hydroxypicolinamide
  • Correlated keywords
    • 11098-76-3 23327-37-9 factor S anti-biotic 1 1754Z3-B Staphylococcus chloramphenicol florfenicol
  • Product Overview:
    Virginiamycin S1 is a macrolide antibiotic that is a component of the virginiamycin complex (Item No. 14503), which also contains virginiamycin M1 (Item No. 9002172).{39373} It is a member of the streptogramin B group of antibiotics, which bind the 50S ribosomal subunit at the peptidyl transferase center to inhibit initiation and translocation.{27765} They show good bactericidal activity against methicillin-resistant S. aureus (MRSA), although resistance in MRSA is conferred by the cfr gene.{27765,28231} Virginiamycin S1 acts synergistically with virginiamycin M1 to irreversibly inhibit protein synthesis in bacteria.{23008}

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