Vinorelbine (tartrate)

Vinorelbine (tartrate)

CAT N°: 21262
Price:

From 92.00 78.20

Vinorelbine is a semisynthetic vinca alkaloid with microtubule destabilizing activity.{24892,28232} It inhibits microtubule polymerization and blocks mitosis at the metaphase/anaphase transition, preventing HeLa cell proliferation with an IC50 value of 1.25 nM.{33560} In in vitro and in vivo models, vinorelbine has demonstrated additive effects when combined with other antimitotic agents to reduce the proliferation of various solid tumor, lymphoma, or lung cancer cell lines.{24892}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (2?,3?,4?,5?,12R,19?)-4-(acetyloxy)-6,7-didehydro-15-[(2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic acid, methyl ester, 2R,3R-dihydroxybutanedioate (1:2)
  • Correlated keywords
    • 892125-21-2 71486-22-1 KW2307 navelbine nor-5′-anhydrovinblastine ditartrate
  • Product Overview:
    Vinorelbine is a semisynthetic vinca alkaloid with microtubule destabilizing activity.{24892,28232} It inhibits microtubule polymerization and blocks mitosis at the metaphase/anaphase transition, preventing HeLa cell proliferation with an IC50 value of 1.25 nM.{33560} In in vitro and in vivo models, vinorelbine has demonstrated additive effects when combined with other antimitotic agents to reduce the proliferation of various solid tumor, lymphoma, or lung cancer cell lines.{24892}

We also advise you