Territorial Availability: Available worldwide directly through Bertin or your local distributor
- Synonyms
- Cadherin-5
- Vascular endothelial cadherin
- Correlated keywords
- VE-Cadherin
- Cad3
- spibio
- spi-bio
- A03144
- Product Overview:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. VE-cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. It acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen.