Valnoctamide

Valnoctamide

CAT N°: 18456
Price:

From 48.00 40.80

Valnoctamide is an isomer of the valproic acid amide, valpromide. It has been marketed as an anxiolytic and sedative compound and suppresses neuropathic pain.{29670,29672} Unlike valpromide, valnoctamide is not metabolized to its acid form, valnoctic acid, in vivo and has no teratogenicity.{29670} It abolishes the activity of myo-inositol-1-phosphate synthase in human brain crude homogenates (Ki = 0.18 mM).{21734} Valnoctamide suppresses electrographic seizures in animal models of status epilepticus, suggesting potential applications in managing epilepsy.{29671}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-ethyl-3-methyl-pentanamide
  • Correlated keywords
    • anxiolytic seizure epilepsy axiquel nirvanil McN X 181 McNX181 NSC32363 NSC34092 valproic valpromide
  • Product Overview:
    Valnoctamide is an isomer of the valproic acid amide, valpromide. It has been marketed as an anxiolytic and sedative compound and suppresses neuropathic pain.{29670,29672} Unlike valpromide, valnoctamide is not metabolized to its acid form, valnoctic acid, in vivo and has no teratogenicity.{29670} It abolishes the activity of myo-inositol-1-phosphate synthase in human brain crude homogenates (Ki = 0.18 mM).{21734} Valnoctamide suppresses electrographic seizures in animal models of status epilepticus, suggesting potential applications in managing epilepsy.{29671}

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