(+)-D-threo–PDMP (hydrochloride)
(+)-D-threo–PDMP (hydrochloride)
(+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP (Item No. 62595).{11392} (+)-D-threo-PDMP is...
€707.00
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€359.00 €305.15
€359.00 €305.15
Tyr-?-CGRP is an N-terminal extended tyrosinated analogue of ?-calcitonin gene-related peptide (?-CGRP; Item No. 24405).{38807} It binds to amylin receptors AMY1 and AMY3 in COS-7 cells expressing the human receptors (IC50s = 141 and 1.86 nM, respectively).{38808} Tyr-?-CGRP also binds to and stimulates cAMP accumulation in rat L6 myocytes (IC50 = 4 nM; EC50 = 12 nM).{38807} It also binds to rat brain and spleen membrane preparations (IC50s = 0.2 and 0.5 nM, respectively), induces positive chronotropic and inotropic effects in isolated right and left guinea pig atria (EC50s = 282 and 74 nM, respectively), and inhibits the twitch response in rat vas deferens (EC50 = 1.9 nM).{38809}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 500 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 124756-98-5 |
| Molecular formula | C172H276N52O51S2 • XCF3COOH |
| Smiles | NC([C@@H](NC([C@@H](NC([C@H](CCCCN)NC([C@H](CO)NC(CNC([C@H](C(C)C)NC([C@H](CC(N)=O)NC([C@@]([C@@H](C)O)([H])NC([C@@H]1CCCN1C([C@H](C(C)C)NC([C@@H](NC([C@H](CC(N)=O)NC([C@H](CC(N)=O)NC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@H](C(C)C)NC(CNC(CNC([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC(CNC([C@@H](NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@]([C@@H](C)O)([H])NC([C@H](C(C)C)NC([C@@H](N2)CSSC[C@H](NC([C@@H](NC([C@@H](N[H])CC3=CC=C(O)C=C3)=O)C)=O)C(N[C@H](C(N[C@]([C@@H](C)O)([H])C(N[C@H](C(N[C@]([C@@H](C)O)([H])C2=O)=O)C)=O)=O)CC(O)=O)=O)=O)=O)=O)CC4=CN=CN4)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)CC6=CC=CC=C6)=O.FC(F)(C(O)=O)F |
| Molecular weight | 3952,5 |
| Formulation | A lyophilized powder |
| Purity | ≥95% |
| Custom code | 3504.00 |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
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