Tunicamycin 16:1 Mixture

Tunicamycin 16:1 Mixture

CAT N°: 28357
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Tunicamycin 16:1 is a mixture of tunicamycin structural isomers that contain a 16-carbon N-acyl chain with variable branching patterns. The N-acyl chain incorporated into tunicamycins, like tunicamycin 16:1, is derived from the same pool of cellular branched-chain fatty acids (BCFAs) in Streptomyces and directly impacts the biological activity of each individual tunicamycin variant.{54724,55467,50054} Purified tunicamycin 16:1 with the iso branching configuration inhibits bacterial phospho-MurNAc-pentapeptide transferase (MraY) with an IC50 value of 0.11 µM.{55467}

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