TTF1 Rabbit Monoclonal Antibody

TTF1 Rabbit Monoclonal Antibody

CAT N°: 32298
Price:

615.00 522.75

Thyroid transcription factor-1 (TTF1) is a member of the NKX2 transcription factor family.{58256,58254} It is expressed in the thyroid, pulmonary epithelium, and hypothalamus, and localized to the nucleus, where it functions as a lineage regulator inducing tissue-specific gene expression.{58256,58255} TTF1 is expressed in the majority of lung adenocarcinomas, acting as a lineage survival oncogene.{58254} However, it also functions as a tumor suppressor and is positively correlated with favorable outcomes in patients with non-small cell lung cancer (NSCLC).{58254,58255} TTF1 is expressed in some breast and ovarian cancers and is correlated with high grade and poorer disease-specific survival, respectively.{58255} Cayman’s TTF1 Rabbit Monoclonal Antibody can be used for immunohistochemistry (IHC) and Western blot (WB) applications.

Territorial Availability: Available through Bertin Technologies only in France

  • Correlated keywords
    • TTF 1 NKX 2 nonsmall
  • Product Overview:
    Thyroid transcription factor-1 (TTF1) is a member of the NKX2 transcription factor family.{58256,58254} It is expressed in the thyroid, pulmonary epithelium, and hypothalamus, and localized to the nucleus, where it functions as a lineage regulator inducing tissue-specific gene expression.{58256,58255} TTF1 is expressed in the majority of lung adenocarcinomas, acting as a lineage survival oncogene.{58254} However, it also functions as a tumor suppressor and is positively correlated with favorable outcomes in patients with non-small cell lung cancer (NSCLC).{58254,58255} TTF1 is expressed in some breast and ovarian cancers and is correlated with high grade and poorer disease-specific survival, respectively.{58255} Cayman’s TTF1 Rabbit Monoclonal Antibody can be used for immunohistochemistry (IHC) and Western blot (WB) applications.

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