Tryptophan Hydroxylase Polyclonal Antibody

CAT N°: 10009396
Price:

680.00 578.00

Tryptophan hydroxylase (TPH) catalyzes the first step in the biosynthesis of serotonin and melatonin.{14424} Thus, expression of TPH can be used as an indicator of the localization of serotonin and melatonin in brain. In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland.{14423} Although TPH catalyzes the same reaction within the Raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis.{14424}

Territorial Availability: Available through Bertin Technologies only in France

  • Correlated keywords
    • hydroxylases catalyzes biosynthesis serotonin melatonin brain mammals neurons Raphe nuclei pineal gland antibodies antisera antiserum WB western blots blotting IHC immunohistochemistry frozen sections proteins diseases immunoblotting
  • Product Overview:
    Tryptophan hydroxylase (TPH) catalyzes the first step in the biosynthesis of serotonin and melatonin.{14424} Thus, expression of TPH can be used as an indicator of the localization of serotonin and melatonin in brain. In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland.{14423} Although TPH catalyzes the same reaction within the Raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis.{14424}

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