<em>trans</em>-10-hydroxy Nortriptyline

trans-10-hydroxy Nortriptyline

CAT N°: 36660
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From 260.00 221.00

trans-10-hydroxy Nortriptyline is an active metabolite of the tricyclic antidepressants amitriptyline (Item No. 15881) and nortriptyline (Item No. 15904).{61943,61944} It is formed from amitriptyline and nortriptyline by the cytochrome P450 (CYP) isoform CYP2D6.{61943} trans-10-hydroxy Nortriptyline inhibits norepinephrine reuptake in rat cortical slices and isolated human plasma (EC50s = 160 and 176 nM, respectively).{61944}

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