Tozadenant

Tozadenant

CAT N°: 28452
Price:

From 92.00 78.20

Tozadenant is an adenosine A2A receptor antagonist (Kis = 11.5 and 6 nM for the human and rhesus monkey receptors, respectively).{47787} It increases the distance traveled and reduces contralateral asymmetry in the open field test in a rat model of Parkinson’s disease induced by 6-OHDA (Item No. 25330) when administered at a dose of 30 mg/kg.{47788} Tozadenant (150 mg/kg) reverses locomotor deficits and restores novel object-stimulated locomotion in a marmoset model of MPTP-induced Parkinson’s disease.{47789}

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