Tizoxanide-d<sub>4</sub>

Tizoxanide-d4

CAT N°: 28533
Price:

414.00 351.90

Tizoxanide-d4 is intended for use as an internal standard for the quantification of tizoxanide (Item No. 13693) by GC- or LC-MS. Tizoxanide is an active metabolite of the antiparasitic nitazoxanide (Item No. 13692).{17926} Tizoxanide is formed from nitazoxanide via deacetylation of nitazoxanide in the stomach. It is active against M. tuberculosis (MIC = 16 µg/ml). It also reduces the growth of the disease-causing parasites L. mexicana and T. cruzi in vitro (IC50s = 6.2 and 17.5 ?M, respectively), inhibits influenza A replication (EC50s = 0.3-1 ?M), and inhibits hepatitis B and hepatitis C virus replication (EC50 = 0.15 ?M for both).{19984,19985,19983}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-hydroxy-N-(5-nitro-2-thiazolyl)-benzamide-3,4,5,6-d4
  • Correlated keywords
    • NSC697856 anti-parasitic Mycobacterium Leishmania Trypanosoma Hep NSC-697856 GCMS LCMS deuterated deuterium flu
  • Product Overview:
    Tizoxanide-d4 is intended for use as an internal standard for the quantification of tizoxanide (Item No. 13693) by GC- or LC-MS. Tizoxanide is an active metabolite of the antiparasitic nitazoxanide (Item No. 13692).{17926} Tizoxanide is formed from nitazoxanide via deacetylation of nitazoxanide in the stomach. It is active against M. tuberculosis (MIC = 16 µg/ml). It also reduces the growth of the disease-causing parasites L. mexicana and T. cruzi in vitro (IC50s = 6.2 and 17.5 ?M, respectively), inhibits influenza A replication (EC50s = 0.3-1 ?M), and inhibits hepatitis B and hepatitis C virus replication (EC50 = 0.15 ?M for both).{19984,19985,19983}

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