Tioconazole

Tioconazole

CAT N°: 26069
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From 55.00 46.75

Tioconazole is an imidazole antifungal that inhibits the growth of various fungi, including C. albicans, C. neoformans, A. fumigatus, and T. rubrum (MICs = 4.7, 0.1, 5.7, and 0.5 µg/ml, respectively).{25584,48062} It inhibits C-14 demethylation of sterols in a cell-free C. albicans homogenate (IC50 = 50-80 nM).{48063} Tioconazole (2% w/v cream) reduces the number of viable Candida cells recovered from the vagina in a mouse model of vaginal candidiasis.{48064} Formulations containing tioconazole have been used in the treatment of vaginal yeast infections.

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