TIM4 Monoclonal Antibody

TIM4 Monoclonal Antibody

CAT N°: 10322
Price:

474.00 402.90

T cell immunoglobulin and mucin domain-containing molecule (TIM4) is a type I transmembrane protein from the TIM gene family that plays a vital role in regulating immune responses, including those in allergy, asthma, transplant tolerance, autoimmunity, and viral infections.{21964} TIM4 is expressed on dendritic cells and macrophages, and these proteins bind tightly to phosphatidylserine on apoptotic cells and enhance their engulfment by macrophages.{15136} It also plays an important role in the proliferation of T helper type 2 cells.{21966} TIM4 is the natural ligand of TIM1, and this binding regulates T cell proliferation.{21967} TIM4 expressing cells also regulate adaptive immunity.{21965}

Territorial Availability: Available through Bertin Technologies only in France

  • Correlated keywords
    • t-cell t cell mucin trans membrane protein immune responses allergy asthma transplant tolerance viral infections dendritic macrophages phosphatidylserine T helper type 2 Th2 immunity TIM-4 TIM 4 TIMs TIMD-4 TIM D4 TIMD4
  • Product Overview:
    T cell immunoglobulin and mucin domain-containing molecule (TIM4) is a type I transmembrane protein from the TIM gene family that plays a vital role in regulating immune responses, including those in allergy, asthma, transplant tolerance, autoimmunity, and viral infections.{21964} TIM4 is expressed on dendritic cells and macrophages, and these proteins bind tightly to phosphatidylserine on apoptotic cells and enhance their engulfment by macrophages.{15136} It also plays an important role in the proliferation of T helper type 2 cells.{21966} TIM4 is the natural ligand of TIM1, and this binding regulates T cell proliferation.{21967} TIM4 expressing cells also regulate adaptive immunity.{21965}

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