Ticlopidine (hydro<wbr/>chloride)

Ticlopidine (hydrochloride)

CAT N°: 20770
Price:

From 48.00 40.80

Ticlopidine is a thienopyridine P2Y12 receptor antagonist.{37611} It inhibits aggregation of human platelets induced by collagen, arachidonic acid (Item No. 90010), and ADP (Item No. 16778; IC50s = 75, 600, and 1,300 ?M, respectively).{37612} It also inhibits ADP-induced aggregation of rat platelets and decreases thrombus weight in vivo in a rat model of arterio-venous shunt thrombosis when administered at a dose of 100 mg/kg.{23697} Ticlopidine (300 mg/kg) inhibits healing of acetic acid-induced gastric ulcers in rats.{37613} Formulations containing ticlopidine have been used in the prevention of thrombotic stroke.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine, monohydrochloride
  • Correlated keywords
    • 55142-85-3 P2Y-12 arteriovenous anti-platelet 4C32 53-32C 5332C Anagregal Caudaline Clid Nichistate Panaldine Panapidin Ticlodone Ticlodox Ticlosin Tiklid ticlid
  • Product Overview:
    Ticlopidine is a thienopyridine P2Y12 receptor antagonist.{37611} It inhibits aggregation of human platelets induced by collagen, arachidonic acid (Item No. 90010), and ADP (Item No. 16778; IC50s = 75, 600, and 1,300 ?M, respectively).{37612} It also inhibits ADP-induced aggregation of rat platelets and decreases thrombus weight in vivo in a rat model of arterio-venous shunt thrombosis when administered at a dose of 100 mg/kg.{23697} Ticlopidine (300 mg/kg) inhibits healing of acetic acid-induced gastric ulcers in rats.{37613} Formulations containing ticlopidine have been used in the prevention of thrombotic stroke.

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