Thimerosal

Thimerosal

CAT N°: 33432
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Thimerosal is a mercurial antimicrobial agent.{61283,61284} It is bacteriostatic against hemolytic streptococci and fungistatic against H. capsulatum, B. dermatitidis, and S. schenckii. Thimerosal (1-250 µM) induces apoptosis in HCN-1A human cortical neurons and various neuroblastoma cells.{18689,61285} In vivo, thimerosal (80 mg/kg, i.p.) induces footpad swelling and dorsal skin contact dermatitis in a mouse model of pseudo-allergic reaction.{61286} Formulations containing thimerosal have been used as antiseptics and preservatives in vaccines.

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