tetranor-<wbr/>PGDM lactone

tetranor-PGDM lactone

CAT N°: 13564
Price:

From 220.00 187.00

Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle.{580} tetranor-PGDM is an abundant urinary metabolite of PGD2 that is detectable both in human and mouse and, as such, is used as a biomarker of PGD2 biosynthesis.{15162} tetranor-PGDM lactone is a closed form of tetranor-PGDM. The formation of tetranor-PGDM lactone in biological samples has not been evaluated.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 8-((4aR,5R,7aS)-2,6-dioxooctahydrocyclopenta[b]pyran-5-yl)-6-oxooctanoic acid
  • Correlated keywords
    • urine PGD2 prostaglandins D2 tetranor PGDM PGs allergic allergy asthma anaphylaxis sleep body temperature inhibits inhibition inhibitor platelets aggregation vascular smooth muscles urinary metabolites humans mouse biomarkers biosynthesis lactones PGD-M t-PGDM t-prostaglandin
  • Product Overview:
    Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle.{580} tetranor-PGDM is an abundant urinary metabolite of PGD2 that is detectable both in human and mouse and, as such, is used as a biomarker of PGD2 biosynthesis.{15162} tetranor-PGDM lactone is a closed form of tetranor-PGDM. The formation of tetranor-PGDM lactone in biological samples has not been evaluated.

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