Terrecyclic Acid

Terrecyclic Acid

CAT N°: 28117
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313.00 266.05

Terrecyclic acid is a sesquiterpene originally isolated from A. terreus with antibiotic and anticancer activity.{46285} It is active against S. aureus, B. subtilis, and M. roseus (MICs = 25, 50, and 25 ?g/ml, respectively). Terrecyclic acid induces a heat shock response, increases levels of reactive oxygen species (ROS), and inhibits NF-?B activity and cell growth in 3T3-Y9-B12 cells.{46286} In vivo, terrecyclic acid (0.1, 1, and 10 mg/ml) reduces the number of ascitic fluid tumor cells in a mouse model of P388 murine leukemia.{46285}

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