Terrecyclic Acid

Terrecyclic Acid

CAT N°: 28117
Price:

From 313.00 266.05

Terrecyclic acid is a sesquiterpene originally isolated from A. terreus with antibiotic and anticancer activity.{46285} It is active against S. aureus, B. subtilis, and M. roseus (MICs = 25, 50, and 25 ?g/ml, respectively). Terrecyclic acid induces a heat shock response, increases levels of reactive oxygen species (ROS), and inhibits NF-?B activity and cell growth in 3T3-Y9-B12 cells.{46286} In vivo, terrecyclic acid (0.1, 1, and 10 mg/ml) reduces the number of ascitic fluid tumor cells in a mouse model of P388 murine leukemia.{46285}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (3aS,4R,7R,7aR)-octahydro-8,8-dimethyl-3-methylene-2-oxo-3a,7-ethano-3aH-indene-4-carboxylic acid
  • Correlated keywords
    • Aspergillus Staphylococcus Bacillus Micrococcus NF?B 3T3Y9 Y9B12 3T3Y9B12 A P-388 anti-biotic cancer
  • Product Overview:
    Terrecyclic acid is a sesquiterpene originally isolated from A. terreus with antibiotic and anticancer activity.{46285} It is active against S. aureus, B. subtilis, and M. roseus (MICs = 25, 50, and 25 ?g/ml, respectively). Terrecyclic acid induces a heat shock response, increases levels of reactive oxygen species (ROS), and inhibits NF-?B activity and cell growth in 3T3-Y9-B12 cells.{46286} In vivo, terrecyclic acid (0.1, 1, and 10 mg/ml) reduces the number of ascitic fluid tumor cells in a mouse model of P388 murine leukemia.{46285}

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