Terazosin (hydro<wbr/>chloride)

Terazosin (hydrochloride)

CAT N°: 20216
Price:

From 165.00 140.25

Terazosin is a potent and selective ?1-adrenergic receptor (?1-AR) antagonist (Kis = 3.28, 0.68, and 1.09 for ?1A-, ?1B- and ?1D-ARs, respectively).{37003} It is selective for ?1- over ?2-AR subtypes (Kis = 1,510, 7.71, and 78.2 nM for A2a-, A2b-, and A2c-ARs, respectively). Terazosin (0.1-30 mg/kg) decreases blood pressure in spontaneously hypertensive rats.{37004} It also decreases blood pressure in anesthetized dogs. Formulations containing terazosin are used to treat hypertension and benign prostatic hyperplasia.{37002,37005}

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