Temozolomide

Temozolomide

CAT N°: 14163
Price:

From 74.00 62.90

Temozolomide (TMZ) is an imidazotetrazine that is converted to a compound capable of alkylating DNA, thus interfering with DNA replication and leading to cytotoxicity in proliferating cells.{21297} TMZ is rapidly and completely absorbed from the gastrointestinal tract after oral administration and readily crosses the blood-brain barrier.{21297} It is effective in a variety of types of cancer, including aggressive brain cancers.{21297,21296,20678}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 3,4-dihydro-3-methyl-4-oxo-imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide
  • Correlated keywords
    • 97716-75-1 cancers DNA damages repairs alkylating agents precursors imidazotetrazine proliferating cells gastrointestinal tracts brain M and B 39831 MBs 39831 MB-39831 MB39831 NSCs 362856 NSC362856 NSC-362856 Schs 52365 Sch-52365 Sch52365 Temodar
  • Product Overview:
    Temozolomide (TMZ) is an imidazotetrazine that is converted to a compound capable of alkylating DNA, thus interfering with DNA replication and leading to cytotoxicity in proliferating cells.{21297} TMZ is rapidly and completely absorbed from the gastrointestinal tract after oral administration and readily crosses the blood-brain barrier.{21297} It is effective in a variety of types of cancer, including aggressive brain cancers.{21297,21296,20678}

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