Tebipenem Pivoxil

Tebipenem Pivoxil

CAT N°: 30613
Price:

80.00 68.00

Tebipenem pivoxil is a prodrug form of the carbapenem antibiotic tebipenem.{54320} Tebipenem pivoxil is metabolized by carboxylesterase (CES) in intestinal epithelial cells to form tebipenem.{54321} Tebipenem pivoxil is active against methicillin-sensitive and -resistant S. aureus (MRSA; MIC90s = ?0.125 and 16 µg/ml, respectively), as well as E. faecalis, E. coli, K. pneumoniae, E. aerogenes, H. influenzae, and P. aeruginosa (MIC90s = 32, 1, 0.5, ?0.125, 0.25, and 64 µg/ml, respectively).{54320} It increases survival in mouse models of sepsis induced by S. aureus, E. coli, or P. aeruginosa when administered at doses of 50 and 100 mg/kg.

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