TCL053

TCL053

CAT N°: 37045
Price:

From 168.00 142.80

TCL053 is an ionizable cationic amino lipid.{66116} It has been used in the generation of lipid nanoparticles (LNPs) and has a pKa value of 6.8. LNPs containing TCL053 and encapsulating mRNA encoding the Cas9 nuclease, in combination with LNPs containing TCL053 and encapsulating single-guide RNA (sgRNA) targeting the Rosa26 locus, have been used to induce CRISPR-mediated gene editing in the mouse gastrocnemius muscle.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-(((4-(dimethylamino)butanoyl)oxy)methyl)-2-((((Z)-tetradec-9-enoyl)oxy)methyl)propane-1,3-diyl (9Z,9’Z)-bis(tetradec-9-enoate)
  • Correlated keywords
    • TCL-053 Cas-9 sg Rosa-26
  • Product Overview:
    TCL053 is an ionizable cationic amino lipid.{66116} It has been used in the generation of lipid nanoparticles (LNPs) and has a pKa value of 6.8. LNPs containing TCL053 and encapsulating mRNA encoding the Cas9 nuclease, in combination with LNPs containing TCL053 and encapsulating single-guide RNA (sgRNA) targeting the Rosa26 locus, have been used to induce CRISPR-mediated gene editing in the mouse gastrocnemius muscle.

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