TASIN-1

TASIN-1

CAT N°: 21155
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From 196.00 166.60

TASIN-1 is a small molecule inhibitor that specifically kills cells with adenomatous polyposis coli (APC) truncations (IC50 = 70 nM) but spares cells with wild-type APC.{33039} TASIN-1 is effective in vivo, inhibiting tumor growth of colorectal cancer (CRC) cells with truncated APC, but not wild-type CRC cells, in a mouse xenograft model.{33039} TASIN-1 decreases cholesterol biosynthesis in APC-truncated cells but not in wild-type APC cells.{33039}

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