TAN 420E

TAN 420E

CAT N°: 28120
Price:

From 330.00 280.50

TAN 420E is a bacterial metabolite originally isolated from Streptomyces.{38266,38265,47368} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (IC50 = 1.3 ?M) and reduces thiobarbituric acid reactive substances (TBARS) in rat liver microsomes by 72% when used at a concentration of 100 ?g/ml.{47368} TAN 420E is active against B. brevis, B. cereus, M. flavus, and S. aureus (MICs = 50-100 ?g/ml).{38266} It is cytotoxic to P388 and KB lymphocytic leukemia cells (EC50s = 0.022 and 0.3 ?g/ml, respectively).{38265}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (15R)-18,21-didehydro-17-demethoxy-18,21-dideoxo-18,21-dihydroxy-15-methoxy-11-O-methyl-geldanamycin
  • Correlated keywords
    • DihydroherbimycinA Di-hydro-herbimycin TAN420E 420 E DP PH Brevibacillus Bacillus Mariniluteicoccus Staphylococcus cyto-toxic P 388 NK 86-0084 NK860084 860084 antibiotic anti biotic
  • Product Overview:
    TAN 420E is a bacterial metabolite originally isolated from Streptomyces.{38266,38265,47368} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (IC50 = 1.3 ?M) and reduces thiobarbituric acid reactive substances (TBARS) in rat liver microsomes by 72% when used at a concentration of 100 ?g/ml.{47368} TAN 420E is active against B. brevis, B. cereus, M. flavus, and S. aureus (MICs = 50-100 ?g/ml).{38266} It is cytotoxic to P388 and KB lymphocytic leukemia cells (EC50s = 0.022 and 0.3 ?g/ml, respectively).{38265}

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