Histone H2A (Xenopus, recombinant)
Histone H2A (Xenopus, recombinant)
Histone H2A is a core histone that forms a dimer with histone H2B.{46631} Two histone H2A/H2B dimers form an octameric...
€818.00
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From €60.00 €51.00
From €60.00 €51.00
The Liver X Receptors (LXR? and LXR?) are nuclear hormone receptors whose native ligands are oxysterols, such as 22(R)-hydroxycholesterol. The LXRs regulate the oxysterol-induced expression of cholesterol 7?-hydroxylase, the rate limiting enzyme of classic bile acid synthesis. T0901317 is a potent and selective agonist for both LXR? and LXR?, with an EC50 of about 50 nM.{8532} T0901317 acting through LXR and in concert with its RXR heterodimerization partner induces the expression of the ABCA1 reverse cholesterol transporter. This acts to increase the efflux of cholesterol from enterocytes and thus inhibit the overall absorption of cholesterol.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 10 mg, 100 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 293754-55-9 |
| Molecular formula | C17H12F9NO3S |
| Smiles | O=S(=O)(c1ccccc1)N(CC(F)(F)F)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F |
| Molecular weight | 481,3 |
| Custom code | 2930.90 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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