SU 16f

SU 16f

CAT N°: 19555
Price:

From 49.00 41.65

SU 16f is a potent inhibitor of platelet-derived growth factor receptor ? (PDGFR?) with an IC50 value of 10 nM.{21720} It also inhibits VEGF receptor 2 (VEGFR2; IC50 = 140 nM). SU 16f selectively inhibits PDGF- over VEFG-, FGF-, and EGF-induced cell proliferation (IC50s = 0.11, 10, 10, and 21.9 ?M, respectively). It also accelerates downregulation of fibroblast genes and increases the yield of beating clusters in human foreskin fibroblasts (HFFs) treated with 15 compounds to induce a cardiac myocyte-like phenotype.{31142}

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