€634.00 €538.90
Stiripentol-d9 is intended for use as an internal standard for the quantification of stiripentol (Item No. 17781) by GC- or LC-MS. Stiripentol is a third-generation antiepileptic compound.{28852} It is a positive allosteric modulator of GABAA receptors, potentiating GABA-mediated activation to a greater extent in receptors expressing ?3 subunits and to a lower extent in those containing ?1 or ? subunits.{48495} It also inhibits GABA reuptake in vitro and increases the release of GABA in neonatal rat hippocampal slices.{28852,48496} Stiripentol (500 µM) inhibits lactate dehydrogenase (LDH), blocking both lactate-to-pyruvate and pyruvate-to-lactate conversions by human LDH1 and LDH5.{28811} Formulations containing stiripentol have been used in the adjunctive treatment of seizures associated with Dravet syndrome.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 1185239-64-8 |
| Molecular formula | C14H9D9O3 |
| Smiles | OC(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])/C=C/C1=CC(OCO2)=C2C=C1 |
| Molecular weight | 243,3 |
| Formulation | A solid |
| Purity | ≥99% deuterated forms (d1-d9) |
| Custom code | 3822.19 |
| UNSPSC code | 12352100 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.
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