SR 95531 (hydro<wbr>bromide)

SR 95531 (hydrobromide)

CAT N°: 14585
Price:

109.00 92.65

SR 95531 is a derivative of ?-aminobutyric acid (GABA) that acts as an antagonist of GABAA receptors (Ki = 74-150 nM).{23068,23065,23067} When administered intravenously, it elicits seizures in mice.{23068} SR 95531 differs in action from bicuculline (Item No. 11727) in that it antagonizes GABA-induced chloride currents but not those induced by pentobarbitone.{23064} It is effective against GABAA receptor isoforms from mice, rats, and humans.{23068,23065,23063}

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