SR 16584

SR 16584

CAT N°: 10683
Price:

From 49.00 41.65

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels in the central and peripheral nervous system. SR 16584 is an antagonist of the ?3?4 nAChR subtype (IC50 = 10.2 ?M).{18814} It shows selective binding of the ?3?4 subtype compared to the ?4?2 and ?7 subtypes (Ki values of 0.508, >100, and >100 ?M, respectively), indicating that it should be a useful tool for receptor subtype studies.{18814}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 3-dihydro-1-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-2H-indol-2-one
  • Correlated keywords
    • antagonists receptors nicotinic acetylcholine receptors neuroscience nAChRs ligands ion channels central peripheral nerves nervous system subtypes SR-16584 SR16584 ?3?4 ?4?2 ?7
  • Product Overview:
    Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels in the central and peripheral nervous system. SR 16584 is an antagonist of the ?3?4 nAChR subtype (IC50 = 10.2 ?M).{18814} It shows selective binding of the ?3?4 subtype compared to the ?4?2 and ?7 subtypes (Ki values of 0.508, >100, and >100 ?M, respectively), indicating that it should be a useful tool for receptor subtype studies.{18814}

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