sPLA<sub>2</sub> (human Type IIA) Polyclonal Antiserum

sPLA2 (human Type IIA) Polyclonal Antiserum

CAT N°: 160502
Price:

474.00 402.90

sPLA2 catalyzes the hydrolysis of phospholipids at the sn-2 position yielding a free fatty acid and a lysophospholipid.{2489} The release of arachidonic acid from membrane phospholipids by PLA2 is believed to be a key step in the control of eicosanoid production within the cell.{1474} Human sPLA2 (Type IIA) is secreted, 14 kDa protein which is dependent on Ca2+ for optimal activity. Human sPLA2 (Type IIA) is 79% homologous to rat platelet and murine Type II sPLA2s. Cayman’s sPLA2 antibody detects a band of approximately 15 kD by Western blot. For other applications, the working concentration of the antiserum must be determined empirically

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