SNC 80

SNC 80

CAT N°: 15599
Price:

From 109.00 92.65

SNC 80 is a selective nonpeptide agonist of the ?-opioid receptor (Ki = 0.18 nM, IC50 = 2.73 nM) that is over 2,000-fold less effective at the ?-opioid receptor.{25516,25513,25515} It effectively activates µ/? receptor heteromers (EC50 = 52.8 nM) but not ?/? or ?/? heteromers.{25524} SNC 80 has antinociceptive as well as pro-convulsant effects in vivo.{25516,25513,25514}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 4-[(R)-[(2S,5R)-2,5-dimethyl-4-(2-propen-1-yl)-1-piperazinyl](3-methoxyphenyl)methyl]-N,N-diethyl-benzamide
  • Correlated keywords
    • receptors agonists opioids pain neurosciences selective delta-opioids .delta.-opioids d-opioids ?-opioids delta .delta. ? d heteromers in vivo antinociceptive anti-nociceptive anti nociceptive pro-convulsants proconvulsants pro convulsants SNCs 80 SNC-80 SNC80 NIHs 10815 NIH10815 NIH-10815 µ/? mu/delta .mu./.delta. µ mu .mu.
  • Product Overview:
    SNC 80 is a selective nonpeptide agonist of the ?-opioid receptor (Ki = 0.18 nM, IC50 = 2.73 nM) that is over 2,000-fold less effective at the ?-opioid receptor.{25516,25513,25515} It effectively activates µ/? receptor heteromers (EC50 = 52.8 nM) but not ?/? or ?/? heteromers.{25524} SNC 80 has antinociceptive as well as pro-convulsant effects in vivo.{25516,25513,25514}

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