SMI-16a

SMI-16a

CAT N°: 29456
Price:

From 140.00 119.00

SMI-16a is a Pim-1 kinase inhibitor (IC50 = 63 nM).{45696} It is selective for Pim-1 over a panel of 60 kinases. SMI-16a (5 ?M) inhibits phosphorylation of the Pim-1 target protein Bad in DU145-Pim cells and inhibits the growth of PC3, DU145, LNCaP, K562, and MV4-11 cancer cells. It induces apoptosis and cell cycle arrest at the G1 phase in DU145 cells.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 5-[(4-propoxyphenyl)methylene]-2,4-thiazolidinedione
  • Correlated keywords
    • Pim1 SMI16a DU145Pim DU-145 PC-3 LNC-aP K-562 MV411 MV-4 411 G
  • Product Overview:
    SMI-16a is a Pim-1 kinase inhibitor (IC50 = 63 nM).{45696} It is selective for Pim-1 over a panel of 60 kinases. SMI-16a (5 ?M) inhibits phosphorylation of the Pim-1 target protein Bad in DU145-Pim cells and inhibits the growth of PC3, DU145, LNCaP, K562, and MV4-11 cancer cells. It induces apoptosis and cell cycle arrest at the G1 phase in DU145 cells.

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