24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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From €55.00 €46.75
SL 01 is a prodrug of gemcitabine (Item No. 11690), the nucleoside analog used intravenously to treat various cancers that was designed for improved oral bioavailability.{24479} SL 01 can inhibit the growth of human non-small cell lung cancer NCI-H460 cells, colon cancer HCT116 cells, and breast cancer MCF-7 cells (IC50s = 0.78, 0.92, and 0.64 ?M, respectively), inducing apoptosis.{24480,24481} In nude mice bearing NCI-H460, HCT116, or MCF-7 cancer cell xenografts, SL 01 at 10-50 ?M/kg has been shown to delay tumor growth.{24480,24481}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 g, 250 mg, 500 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 26049-94-5 |
| Molecular formula | C18H18ClNO3 |
| Smiles | O=C(CCl)[C@@H](NC(OCC1=CC=CC=C1)=O)CC2=CC=CC=C2 |
| Molecular weight | 331,8 |
| Custom code | 2922.19 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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