Se-Aspirin

Se-Aspirin

CAT N°: 19315
Price:

From 48.00 40.80

Se-Aspirin is a hybrid of selenium and a nonsteroidal anti-inflammatory drug that has been shown to reduce the viability of different cancer cell lines, particularly colorectal cancer (CRC) cells (IC50 = 3.4 µM).{31298} It can inhibit the cell cycle in G1 and G2/M phases and induce apoptosis by activating caspase 3/7 and PARP cleavage.{31298} Long-term exposure to Se-Aspirin is reported to cause an increase in intracellular reactive oxygen species levels in CRC cells.{31298}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • selenocyanic acid, 2-[[2-(acetyloxy)benzoyl]amino]ethyl ester
  • Correlated keywords
    • NSAID anticancer colon anti-cancer nonsteroidal anti-inflammatory drug antiinflammatory hybrid colorectal cell CRC ROS non-steroidal
  • Product Overview:
    Se-Aspirin is a hybrid of selenium and a nonsteroidal anti-inflammatory drug that has been shown to reduce the viability of different cancer cell lines, particularly colorectal cancer (CRC) cells (IC50 = 3.4 µM).{31298} It can inhibit the cell cycle in G1 and G2/M phases and induce apoptosis by activating caspase 3/7 and PARP cleavage.{31298} Long-term exposure to Se-Aspirin is reported to cause an increase in intracellular reactive oxygen species levels in CRC cells.{31298}

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