Scopolin

Scopolin

CAT N°: 33874
Price:

From 92.00 78.20

Scopolin is a coumarin glucoside form of scopoletin (Item No. 20042) that has been found in O. africana and has anti-inflammatory activity.{62174,57033,62175} It decreases the production of prostaglandin E2 (PGE2; Item No. 14010) and leukotriene C4 (LTC4; Item No. 20210) induced by A23187 (Item No. 11016) in isolated mouse peritoneal macrophages when used at a concentration of 100 µM.{57033} Scopolin (50 and 100 mg/kg) reduces synovial inflammation and fibrosis, as well as bone and cartilage erosion, in the inflamed joints in a rat model of rheumatoid arthritis induced by complete Freund’s adjuvant and M. butyricum.{62175}

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