SB 277011A (hydro<wbr>chloride)

SB 277011A (hydrochloride)

CAT N°: 11982
Price:

From 66.00 56.10

SB 277011A is an antagonist of the dopamine D3 receptor (pKi = 8.0) that is at least 100-fold selective for D3 over other monoamine receptors (pKis = 6.0, 5.0, and 2, 5-HT1D and 5-HT1B respectively).{31910,31909,31908} It has high oral bioavailability and enters the central nervous system of the rat.{31910} SB 277011A has been shown to have potential benefits in animal models of schizophrenia and Parkinson’s disease.{31909,31907}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-[trans-4-[2-(6-cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-4-quinolinecarboxamide, dihydrochloride
  • Correlated keywords
    • SB277011A HCl SB-277011-A SB277011-A D3 dopamine CNS D-3
  • Product Overview:
    SB 277011A is an antagonist of the dopamine D3 receptor (pKi = 8.0) that is at least 100-fold selective for D3 over other monoamine receptors (pKis = 6.0, 5.0, and 2, 5-HT1D and 5-HT1B respectively).{31910,31909,31908} It has high oral bioavailability and enters the central nervous system of the rat.{31910} SB 277011A has been shown to have potential benefits in animal models of schizophrenia and Parkinson’s disease.{31909,31907}

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