24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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From €48.00 €40.80
Ketoprofen (Item No. 10006661) is a non-selective, non-steroidal, anti-inflammatory drug exhibiting IC50 values of 0.5 and 2.33 µM for human recombinant COX-1 and COX-2 (Item No. 60122), respectively.{1286} Ketoprofen is commonly used in vivo as a racemic mixture of (R)- and (S)-enantiomers. (S)-Ketoprofen is a potent inhibitor of COX-1 and COX-2 (IC50s = 1.9 and 27 nM, respectively), whereas the (R)-enantiomer is 100 to 1,000 times less potent.{27037,7889} Notably, (S)-ketoprofen is known to be formed from the (R)-enantiomer in several animal species, except in humans and guinea pigs.{7889} Also, the pharmacokinetics of ketoprofen enantiomers and their glucuronide metabolites are altered in humans with rheumatoid arthritis or renal disease.{27035,27036}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 g, 100 mg, 5 g, 500 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 22161-81-5 |
| Molecular formula | C16H14O3 |
| Smiles | O=C(C1=CC=CC([C@H](C)C(O)=O)=C1)C2=CC=CC=C2 |
| Molecular weight | 254,3 |
| Custom code | 2918.99 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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