Ro 25-<wbr/>6981 (maleate)

Ro 25-6981 (maleate)

CAT N°: 14578
Price:

From 85.00 72.25

Ro 25-6981 (maleate) is a potent, selective activity-dependent blocker of NMDA receptors containing the NR2B subunit (IC50s = 9 nM and 52 ?M for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A, respectively).{22852} Ro 25-6981 (maleate) displays neuroprotectant effects in vitro, protecting cortical neurons against glutamate toxicity and combined oxygen and glucose deprivation with IC50 values of 0.4 and 0.04 ?M, respectively.{22852}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • ?R-(4-hydroxyphenyl)-?S-methyl-4-(phenylmethyl)-1-piperidinepropanol, 2Z-butenedioate
  • Correlated keywords
    • 169274-78-6 antagonists NMDA receptors NR2B subunits neuroprotections potent NR2B-selective selectives NR1C/NR2B NR1C/NR2A NR1C NR2B NR2A glutamates toxicity oxygens glucose deprivations Ro-25-6981 Ro-256981 Ro-25 6981 Ro25-6981 Ro256981 Ro25 Ros 256981 toxic deprived blockers cloned clones neuroprotectants in vitro cortical neurons activity-dependent activity dependents blocks Glu oxygen O2 N-methyl-D-aspartate
  • Product Overview:
    Ro 25-6981 (maleate) is a potent, selective activity-dependent blocker of NMDA receptors containing the NR2B subunit (IC50s = 9 nM and 52 ?M for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A, respectively).{22852} Ro 25-6981 (maleate) displays neuroprotectant effects in vitro, protecting cortical neurons against glutamate toxicity and combined oxygen and glucose deprivation with IC50 values of 0.4 and 0.04 ?M, respectively.{22852}

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