24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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From €48.00 €40.80
Rifampicin is a rifamycin antibiotic and inhibitor of bacterial RNA polymerase (IC50 = 0.01 ?g/ml for the E. coli enzyme).{23992} It inhibits the growth of M. tuberculosis H37Rv in mouse peritoneal macrophages (MIC = 0.8 ?g/ml) as well as clinical isolates of various species of Staphylococcus, Streptococcus, Haemophilus, and Neisseria (MICs = 0.009-1.4 ?g/ml).{40531,32022} Rifampicin increases survival in a mouse model of tuberculosis infection.{32022} It is also an agonist of the human pregnane X receptor (PXR; EC50 = ~2 ?M).{23996} Formulations containing rifampicin have been used in the treatment of tuberculosis and meningococcal carriers.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 g, 100 mg, 5 g, 500 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 13292-46-1 |
| Molecular formula | C43H58N4O12 |
| Smiles | OC1=C2C(C(O)=C(C)C(O[C@]3(C)O/C=C/[C@H](OC)[C@@H](C)[C@]([C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C)C(N4)=O)(OC(C)=O)[H])=C2C3=O)=C(O)C4=C1/C=N/N5CCN(C)CC5, OC1=C2C(C(O)=C(C)C(O[C@]3(C)O/C=C/[C@H](OC)[C@@H](C)[C@]([C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C)C(N4)=O)(OC(C)=O)[H])=C2C3=O)=C(O)C4=C1/C=N/N5CCN(C)CC5, OC1=C2C(C(O)=C(C)C(O[C@]3(C)O/C=C/[C@H](OC)[C@@H](C)[C@]([C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C)C(N4)=O)(OC(C)=O)[H])=C2C3=O)=C(O)C4=C1/C=N/N5CCN(C)CC5, OC1=C2C(C(O)=C(C)C(O[C@]3(C)O/C=C/[C@H](OC)[C@@H](C)[C@]([C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C)C(N4)=O)(OC(C)=O)[H])=C2C3=O)=C(O)C4=C1/C=N/N5CCN(C)CC5 |
| Molecular weight | 823 |
| Custom code | 2933.59 |
| Formulation | A crystalline solid |
| Purity | ≥90% |
| UNSPSC code | 12352100 |
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