Rifampicin

Rifampicin

CAT N°: 14423
Price:

48.00 40.80

Rifampicin is a rifamycin antibiotic and inhibitor of bacterial RNA polymerase (IC50 = 0.01 ?g/ml for the E. coli enzyme).{23992} It inhibits the growth of M. tuberculosis H37Rv in mouse peritoneal macrophages (MIC = 0.8 ?g/ml) as well as clinical isolates of various species of Staphylococcus, Streptococcus, Haemophilus, and Neisseria (MICs = 0.009-1.4 ?g/ml).{40531,32022} Rifampicin increases survival in a mouse model of tuberculosis infection.{32022} It is also an agonist of the human pregnane X receptor (PXR; EC50 = ~2 ?M).{23996} Formulations containing rifampicin have been used in the treatment of tuberculosis and meningococcal carriers.

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