Ramoplanin Complex

Ramoplanin Complex

CAT N°: 28189
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From 66.00 56.10

Ramoplanin complex is a mixture of ramoplanin A1, -A2, and -A3 originally isolated from Actinoplanes that has antibacterial activity.{46853,46854,46855} Ramoplanin complex is active against clinical isolates of the Gram-positive bacteria S. aureus, S. pyogenes, S. pneumoniae, and S. faecalis (MICs = 0.016-2 µg/ml) but not Gram-negative bacteria or C. albicans (MICs = ?128 µg/ml).{46854} It inhibits cell wall synthesis in B. subtilis when used at a concentration of 0.5 µg/ml.{46853} Ramoplanin complex is effective against systemic S. pyogenes, S. pneumoniae, and S. aureus infections in mice with ED50 values of 0.081, 0.14, and approximately 25 mg/kg per day, respectively.

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