<em>rac</em>-Desethyl Oxybutynin (hydro<wbr/>chloride)

rac-Desethyl Oxybutynin (hydrochloride)

CAT N°: 34262
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From 119.00 101.15

rac-Desethyl oxybutynin is an active metabolite of the muscarinic acetylcholine receptor (mAChR) antagonist oxybutynin (Item No. 23825).{61451,61452,61453} rac-Desethyl oxybutynin is formed from oxybutynin by the cytochrome P450 (CYP) isoform CYP3A4.{61452} It binds to mAChRs in isolated rat bladder, submaxillary gland, heart, and colon with Ki values of 5.38, 3.12, 16, and 5.59 nM, respectively. rac-Desethyl oxybutynin (0.4 and 0.8 mg/kg) reduces micturition pressure in rats.{61453}

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