(R)-IMPP

(R)-IMPP

CAT N°: 20861
Price:

From 109.00 92.65

(R)-IMPP is a cell-permeable inhibitor of the secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9; IC50 = 4.8 µM).{32414} It promotes the uptake of LDL cholesterol in hepatoma cells by increasing LDL receptor levels.{32414} (R)-IMPP apparently impairs PCSK9 secretion by causing transcript-dependent inhibition of PCSK9 translation.{32414}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-1-isoquinolinyl-4-methoxy-N-(3R)-3-piperidinyl-benzenepropanamide
  • Correlated keywords
    • PCSK-9 low density lipoprotein
  • Product Overview:
    (R)-IMPP is a cell-permeable inhibitor of the secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9; IC50 = 4.8 µM).{32414} It promotes the uptake of LDL cholesterol in hepatoma cells by increasing LDL receptor levels.{32414} (R)-IMPP apparently impairs PCSK9 secretion by causing transcript-dependent inhibition of PCSK9 translation.{32414}

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