(R)-(+)-<wbr/>BAY-<wbr/>K-<wbr/>8644

(R)-(+)-BAY-K-8644

CAT N°: 15263
Price:

From 165.00 140.25

BAY-K-8644, originally described as a modulator of potential operated calcium channels, exists as two enantiomers that have opposite actions.{24672,24674,24673} (R)-(+)-BAY-K-8644 is an L-type channel blocker that has negative inotropic and vasodilatory effects at 1 ?M.{24675,24676,24673} Intracerebroventricular administration of this enantiomer has no effect on motor function in mice, whereas (S)-(?)-BAY-K-8644 impairs rotarod and motor activity, an effect that is blocked by (R)-(+)-BAY-K-8644.{24674}

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