Quinolinic Acid

Quinolinic Acid

CAT N°: 14941
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From 48.00 40.80

Quinolinic acid is an endogenous agonist at NMDA receptors that is generated through the metabolism of tryptophan in the kynurenine pathway.{23856} By overactivating NMDA receptors, quinolinic acid produces neurotoxicity, which has been implicated in certain neurodegenerative disorders.{20572} Quinolinic acid can also generate reactive oxygen species, has immunomodulatory actions, and promotes the formation of hyperphosphorylated tau proteins.{6411,5945,23005}

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