PTP Inhibitor III

PTP Inhibitor III

CAT N°: 19059
Price:

From 54.00 45.90

PTP Inhibitor III is an ?-haloacetophenone derivative that acts as a photoreversible covalent inhibitor of protein tyrosine phosphatases (PTPs).{31401} It binds the catalytic domain of SHP-1 (Ki = 184 µM) and covalently reacts with free thiols, a reaction that is reversible with irradiation (350 nm). PTP Inhibitor III is cell permeable and inhibits a broad range of PTPs.{31402}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-[4-(2-bromoacetyl)phenoxy]-acetic acid
  • Correlated keywords
    • ?-haloacetophenone a-haloacetophenone PTP SHP-1 SHP1 protein tyrosine phosphatase Src homology region 2 domain-containing
  • Product Overview:
    PTP Inhibitor III is an ?-haloacetophenone derivative that acts as a photoreversible covalent inhibitor of protein tyrosine phosphatases (PTPs).{31401} It binds the catalytic domain of SHP-1 (Ki = 184 µM) and covalently reacts with free thiols, a reaction that is reversible with irradiation (350 nm). PTP Inhibitor III is cell permeable and inhibits a broad range of PTPs.{31402}

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