PtdIns-<wbr/>(3,5)-<wbr/>P<sub>2</sub> (1,2-<wbr/>dipalmitoyl) (sodium salt)

PtdIns-(3,5)-P2 (1,2-dipalmitoyl) (sodium salt)

CAT N°: 10008398
Price:

From 94.00 79.90

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.{4096,8344} Phosphatidylinositol (PtdIns)-(3,5)-P2 (1,2-dipalmitoyl) (sodium salt) is a synthetic analog of natural PtdIns featuring saturated C16:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol stereochemistry as that of the natural compound. PtdIns-(3,5)-P2 is rapidly synthesized from PtdIns-(3)-P1 in yeast when a PtdIns-(3)-P5-hydroxy kinase is activated during hyperosmotic conditions.{11568} PtdIns-(3,5)-P2 is also present in mammalian cells, such as monkey COS-7 cells, where a similar biosynthetic route has been demonstrated.{11568}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 1-(1,2R-dihexadecanoylphosphatidyl)inositol-3,5-bisphosphate, trisodium salt
  • Correlated keywords
    • phosphatidylinositols diphosphates phospholipids phophorylation signal transduction IP3 diacylglycerol DAG PIP1 PIP2 PIP3 PLC PLD 214282-36-7
  • Product Overview:
    The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.{4096,8344} Phosphatidylinositol (PtdIns)-(3,5)-P2 (1,2-dipalmitoyl) (sodium salt) is a synthetic analog of natural PtdIns featuring saturated C16:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol stereochemistry as that of the natural compound. PtdIns-(3,5)-P2 is rapidly synthesized from PtdIns-(3)-P1 in yeast when a PtdIns-(3)-P5-hydroxy kinase is activated during hyperosmotic conditions.{11568} PtdIns-(3,5)-P2 is also present in mammalian cells, such as monkey COS-7 cells, where a similar biosynthetic route has been demonstrated.{11568}

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