PROTAC(H-PGDS)-7

PROTAC(H-PGDS)-7

CAT N°: 35561
Price:

From 297.00 252.45

PROTAC(H-PGDS)-7 is a proteolysis-targeting chimera (PROTAC) comprised of the hematopoietic prostaglandin D synthase (H-PGDS) inhibitor TFC-007 (Item No. 17971) and the cereblon inhibitor pomalidomide (Item No. 19877).{62523} It induces degradation of H-PGDS in KU812 cells with a 50% degradation concentration (DC50) value of 17.3 pM, as well as decreases the production of prostaglandin D2 (PGD2) in the same cells.

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